Please make sure you are using the latest version of WinSCP and than verify MD5 or SHA1 checksum of your copy of winscp.exe against WinSCP 5.1.4 release notes:
https://beta.winscp.net/download/winscp514readme.txt

I too have this URL on my Win XP laptop. I have seen multiple copies within one view-window. What do I do About it? I have anti-virus, firewall, etc.

WinSCP definitelly does not connect there on it's own. Unless your copy is infected by virus.

Hi,
when we run winscp in cli-script mode, every connection initiated this way creates also connection to vip1.g-anycast1.cachefly.net:80. Guys from security told as that website vip1.g-anycast1.cachefly.net belongs to a listed malicious host. In windows gui this problem does not come up. This seems like a malware then. May I ask what does cause this ? We ran malware checks but nothing has been found.

System is windows 2003 R2 SP2

thank you for answer

Robert